![]() ![]() By studying ants, Bonasio and colleagues, including Shelley Berger, also at the University of Pennsylvania, wanted to understand how turning certain genes "on" or "off" affects brain function and behavior. And, yet, it is the same genetic instructions that give rise to these very different social roles and behaviors. In an ant colony, workers maintain the colony by finding food and fighting invaders, whereas the queen's main task is to lay eggs. We determined that, in ants, Kr-h1 curbs brains' plasticity by preventing inappropriate gene activation." ![]() "This process, which also takes place in human brains-think about the changes in behavior during adolescence-is crucial to survival, but the molecular mechanisms that control it are not fully understood. "Animal brains are plastic that is, they can change their structure and function in response to the environment," says Roberto Bonasio of the University of Pennsylvania Perelman School of Medicine.
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